Poliovirus induces Bax - dependent cell death mediated by 1 c - Jun NH 2 - terminal kinase 2 3
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Poliovirus induces Bax-dependent cell death mediated by c-Jun NH2-terminal kinase.
Poliovirus (PV) is the causal agent of paralytic poliomyelitis, a disease that involves the destruction of motor neurons associated with PV replication. In PV-infected mice, motor neurons die through an apoptotic process. However, mechanisms by which PV induces cell death in neuronal cells remain unclear. Here, we demonstrate that PV infection of neuronal IMR5 cells induces cytochrome c release...
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تاریخ انتشار 2007